Enforcement of intellectual property rights in Africa is not always a straightforward task. Plans crafted with reference only to enforcement in developed countries will not be a perfect fit to the African situation. Still, there are possible solutions to the issue of counterfeiting and piracy in Africa. Protective mechanisms are a reality. Passionate professionals both within the government and among law practitioners are eager to learn and for the current system to evolve into one which is efficient, and which adequately protect the African consumer from the dangers of counterfeiting. Our final word of advice to right holders would therefore be to surround yourself with professionals who know the continent and who will be able to craft the best possible strategy aligned with expectations and budget.